Lavie_edit.qxp 5/8/08 12:08 Page 74
Cardiac Rehabilitation
Figure 3: Prevalence of Depression Before and After Rehabilitation Figure 6: Cumulative Hazard Curves for Mortality in Patients
in Younger and Elderly Coronary Heart Disease Patients Who Were Depressed and Non-depressed After Formal Cardiac
Rehabilitation and Exercise Training
25
23%
Before rehab
0.35
After rehab
19%
20
0.30
Depressed
p<0.0001 p<0.0001
0.25
15
Non-depressed
c
e (%)
0.20
alen
p<0.0001
0.15
Prev
10
Cumulative hazard (%)
6% 0.10
5
4%
0.05
0
0.00
Young (n=104) Elderly (n=260) 0123456
Time (years)
Data obtained with permission from Lavie CJ, Milani RV, 2006.
26
Reproduced with permission
from Lavie CJ, et al., 2007.
27
Reproduced with permission from Milani RV, Lavie CJ, 2007.
28
Figure 4: Prevalence of Hostility Before and After Rehabilitation in Figure 7: Prevalence of Mortality During Mean 3.5-year Follow-up
Young and Elderly Coronary Heart Disease Patients in Control Depressed Patients (Who Attended Cardiac Rehabilitation
and Exercise Training) Compared with ‘Active’ Depressed Patients
14
(Who Did Not)
13%
Before rehab
12
After rehab
35
p=0.0005
10
30
p<0.01
8 25
c
e (%)
6%
alen
6
20
5%
Prev p<0.05
4
Mortality (%) 15
2%
10
2
5
0
Young (n=104) Elderly (n=260)
0
Control Treatment
Data obtained with permission from Lavie CJ, Milani RV, 2006.
26
Reproduced with permission
from Lavie CJ, et al., 2007.
27 Reproduced with permission from Milani RV, Lavie CJ, 2007.
28
Figure 5: Prevalence of Anxiety Before and After Rehabilitation in Figure 8: Depression and Mortality in Patients Who Did Not
Young and Elderly Coronary Heart Disease Patients Improve Exercise Capacity, Those with Mild Improvements, and
Those with High Improvements Following Cardiac Rehabilitation
30
and Exercise Training
28%
Before rehab
After rehab
25
VO
2
loss Mild VO
2
gain High VO
2
gain
n=102 n=135 n=285
20
Mortality = 15% Mortality = 6% Mortality = 4%*
20
p=NS p=0.004 p<0.001
p<0.0001
14%
16
c
e (%) 15
p<0.05
alen c
e (%)
12
9% 9%
Prev 10 alen
Prev
8
5
4
0
0
Young (n=104) Elderly (n=260)
Baseline Follow-up Baseline Follow-up Baseline Follow-up
depressed depressed depressed depressed depressed depressed
Data obtained with permission from Lavie CJ, Milani RV, 2006.
26
Reproduced with permission
from Lavie CJ, et al., 2007.
27
Reproduced with permission from Milani RV, Lavie CJ, 2007.
28
74 US CARDIOLOGY
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