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Descemet’s Stripping Automated Endothelial Keratoplasty – A Review
epithelial downgrowth have been treated successfully with lenticule
exchange, mechanical scraping and irrigation and aspiration of Anita M Hwang is a Resident in the Department of
residual epithelial cells.
56–58 Ophthalmology and Visual Science at Yale University
School of Medicine. She completed her MD at the State
University of New York at Buffalo and her MS in
Other complications include pupillary block, steroid-induced physiology and biophysics at Georgetown University.
glaucoma, suprachoroidal haemorrhage, infectious donor-to-host
She completed her ophthalmology residency at the Yale
Eye Center and is a Fellow in Cornea, External Disease
transmission of fungal pathogen, cystoid macular oedema and retinal
and Refractive Surgery at the Doheny Eye Institute of
detachment. Air bubble trauma to endothelial cells has also been the University of Southern California.
described in an ex vivo study.
59
Jimmy K Lee is Director of Cornea and Refractive Surgery
Future
at the Yale Eye Center. He specialises in laser vision
correction surgery; his surgical expertise also includes
DMEK is currently under investigation.
60
This procedure involves
cataract surgery with presbyopia or astigmatism
implantation of isolated Descemet’s membrane and endothelial cells
correction and corneal transplantation. Dr Lee’s research
in the host cornea through a self-sealing 3.5mm clear corneal incision.
interests are new technologies in refractive surgery and
improving surgical techniques for Descemet’s stripping
endothelial keratoplasty. A member of the American
A study of 50 DMEK procedures by Ham et al. conveyed promising
Academy of Ophthalmology (AAO) and the American
results: >95% had BCVA better than 20/40 (≥0.5) and 75% had BCVA
Society of Cataract and Refractive Surgery (ASCRS), he has published many peer-
reviewed articles, is a scientific reviewer for numerous ophthalmological journals and has
better than 20/25 (≥0.8). They also showed faster visual
given important lectures on refractive surgery and corneal transplantation at national
rehabilitation (within one to three months) and less refractive
scientific meetings. Dr Lee graduated from Johns Hopkins University and obtained his MD
shift.
61
As these procedures are refined with innovative advances in
from Cornell University Medical College. Following his residency at Albert Einstein
Montefiore Hospital, he completed a fellowship in cornea, external diseases and
tissue handling, the sole replacement of cultured endothelial cells
refractive surgery at the Wilmer Eye Institute of The Johns Hopkins Hospital.
with faster visual rehabilitation may be in the near future. n
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EUROPEAN OPHTHALMIC REVIEW 73
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