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New Trends in the Management of Inflammatory Choroidal Neovascularisation
Regarding non-infectious uveitis, the treatment strategy should be action. Similarly, PDT seems to be no match for anti-VEGF drugs, and
aimed at controlling inflammation with the help of corticosteroids, recent evidence directs the clinician to use these new types of
usually given systemically but sometimes locally in unilateral disease, therapy. However, as for all other methods evaluated, these results
and/or immunosuppressive agents. Corticosteroids with or without are still only based on case reports or small series. For these reasons,
immunosuppressants are also suggested for CNV associated with further study – possibly multicentre, randomised controlled trials –
apparent inactive inflammatory disease: subclinical inflammation can be are mandatory to validate these preliminary results. n
present and can create the conditions for the pathogenesis of CNV.
78,79
Piergiorgio Neri is Head of the Ocular Immunology Unit
Additional therapies aimed directly at the neovascular process are
at the Ospedali Riuniti di Ancona. In 2006 he was
recommended, particularly in those cases showing aggressive Visiting Professor in Uveitis at Moorfields Eye Hospital,
behaviour. If steroids with or without immunosuppressive therapy
London. He is the author or co-author of more than 80
national and international publications. Dr Neri
show an insufficient response, anti-VEGF therapy should be
graduated from the University of Ancona Medical
rapidly introduced. School in 2000. He was an Honorary Research Fellow in
Uveitis at the Eye Department of the University of
Aberdeen in 2002, obtained a specialist diploma in
Argon laser photocoagulation should probably be avoided, even in
ophthalmology at the University of Ancona in 2004 and completed his PhD in
CNV outside the fovea, because intravitreal administration of anti- neurosciences at the University of Ancona in 2007.
VEGF therapy seems be more effective and have a longer-lasting
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EUROPEAN OPHTHALMIC REVIEW 97
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