Parks_EU Neurology 10/03/2010 10:19 Page 119
Reduction of Surgical-site Infections in Neurosurgery
improved by the production of a sterile surface. The risk of surgical- sizes become too large for such a study and the decision to use a
site infection is proportional to the number of residual bacteria at the given agent must rest on other information.
wound site, so a reduction in skin bacterial density will be associated
with a concomitant reduction in surgical-site infection. In any The cumulative in vitro and in vivo evidence related to wound
situation, a randomised prospective clinical study generally carries contamination and extensive clinical experience with implanted
the highest evidence of proof of efficacy of a given treatment neurosurgical devices illustrate the utility of using 3M™Ioban™2 as
regimen. However, in the presence of low infection rates, sample part of an infection prevention regimen within neurosurgery. n
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