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Dual Task Interference in Parkinson’s Disease
tasks. Some neural resources might be shared by the component
Tao Wu is an Associate Professor of Neurobiology in the
tasks in order to execute the dual task efficiently.
Department of Neurobiology at the Beijing Institute of
Geriatrics, Xuanwu Hospital. His main research interests
Our studies demonstrated that practice can diminish dual task
are using functional neuroimaging methods and other
techniques of clinical neurophysiology to understand
interference and improve performance in PD patients. Moreover,
the physiology of normal human voluntary movement
dual task interference in PD is due to multiple reasons: first, the and the pathophysiology of different movement
limitation of attentional resources capacity is exceeded; second, PD
disorders, especially Parkinson’s disease.
patients perform the tasks less automatically compared with
Mark Hallett is Chief of the Human Motor Control
normal subjects; and third, the central executive may be defective
Section in the Intramural Program of the National
in PD. These findings are really helpful to our understanding of dual Institute of Neurological Disorders and Stroke at the
task interference in PD. However, our knowledge of this
National Institutes of Health (NIH). His laboratory
investigates mechanisms of normal human movement
phenomenon is still far from complete. For example, why PD
and the pathophysiology of movement disorders. Dr
patients have difficulty in switching attentional resource between Hallett is an Associate Editor of Brain and Editor in Chief
tasks is unclear, and the central mechanism of this problem needs
of World Neurology.
further investigation. n
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