Contents


Foreword Zoran Rankovic Senior Research Fellow, and Associate Director in Medicinal Chemistry, Merck Research Laboratories, UK Technology and Innovation


Quality Management During the Manufacture of Sanal® P – A High-quality Pharmaceutical Salt


Horst Berkhahn,1 Karen Søgaard Madsen2 and Claudia Borchard-Tuch3


1. Educated Chemist, and Technical Service Manager; 2. Chemical Engineer, and Quality Assurance Manager, AkzoNobel Salt Specialties, Mariager; 3. Medical Doctor, Information Scientist and Medical Writer


A Multimode Cellular Platform for Investigating the G-protein-coupled Receptor Signalling Network


Jean-Luc Tardieu Product Manager, Cisbio Bioassays


Applying Pluripotent Stem Cells in Drug Discovery Matthias Steger


Global Licensing Director, Stem Cell Collaborations, Roche, Basel Biomarkers


Personalised Medicine and the Future of Healthcare – Reflections on the Role of Biomarkers


Klaus Lindpaintner


Vice President, Research and Development, and Chief Scientific Officer, SDIX Medicare and Biomarkers – What Does the Future Look Like?


Bruce Quinn Senior Health Policy Specialist, Foley Hoag LLP Disease and Targets


Maximising RNA Interference Specific Knockdown with Minimal Off-target Effects Lingamanaidu V Ravichandran1


and Lesslie Beauchamp2


1. Staff Scientist; 2. Senior Scientist, Research and Development, Life Technologies, Austin, Texas The GPR37/PAEL Receptor – Finding a Way to the Cell Surface


Priyanka Dutta, Debadutta Deb, Leila Dargahi, Davor Ivankovic and Kumlesh K Dev


Molecular Neuropharmacology, Department of Physiology, Trinity College Institute of Neuroscience, Trinity College Dublin


Contract Manufacturing and Outsourcing


Business Expansion in Brazil Nycomed


Stem Cells


Induced Pluripotent Stem Cells – A New Wave of Tools for Drug Discovery Chris Parker


Chief Commercial Officer, Cellular Dynamics International, Inc. 4 42 40 30 27 23 18 14 10 8


36


DRUG DISCOVERY


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