Emerging Biomarkers for the Early Detection of Acute Kidney Injury 1. 2. 3.
Murray PT, Devarajan P, Level AS, et al., A framework and key research questions in AKI diagnosis and staging in different environments, Clin J Am Soc Nephrol, 2008;3:864–8.
Devarajan P, Update on mechanisms of ischemic acute kidney injury, J Am Soc Nephrol, 2006;17:1503–20.
Nickolas TL, Barasch J, Devarajan P, Biomarkers in acute and chronic kidney disease, Curr Opin Nephrol Hypertens, 2008;17:127–32.
4. Devarajan P, Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of kidney disease, Scand J Clin Lab Invest, 2008;68:89–94.
5. Devarajan P, Neutrophil gelatinase-associated lipocalin – an emerging troponin for kidney injury, Nephrol Dial Transplant, 2008;23(12):3737–43.
6. 7. 8. 9. 10. 11. 12. 13.
Parikh CR, Devarajan P, New biomarkers of acute kidney injury, Crit Care Med, 2008;36(Suppl. 4):159–65.
Uchino S, Kellum JA, Bellomo R, et al., Acute renal failure in critically ill patients: a multinational, multicenter study, JAMA, 2005;294(7):813–8.
Chertow GM, Soroko SH, Paganini EP, et al., Mortality after acute renal failure: models for prognostic stratification and risk adjustment, Kidney Int, 2006;70:1120–6.
Hoste EA, Kellum JA, RIFLE criteria provide robust assessment of kidney dysfunction and correlate with hospital mortality, Crit Care Med, 2006;34(7):2016–7.
Radhakrishnan J, Kiryluk K, Acute renal failure outcomes in children and adults, Kidney Int, 2006;69(1):17–9.
Ympa YP, Sakr Y, Reinhart K, Vincent JL, Has mortality from acute renal failure decreased? A systematic review of the literature, Am J Med, 2005;118(8):827–32.
Bellomo R, The epidemiology of acute renal failure: 1975 versus 2005, Curr Opin Crit Care, 2006;12(6):557–60.
Fischer MJ, Brimhall BB, Lezotte DC, Glazner JE, Parikh CR, Uncomplicated acute renal failure and hospital resource utilization: a retrospective multicenter analysis, Am J Kidney Dis, 2005;46(6):1049–57.
14. 15. 16. 17. 18. 19. 20. 21. 22.
Doi K, Yuen PS, Eisner C, et al., Reduced production of creatinine limits its use as marker of kidney injury in sepsis, J Am Soc Nephrol, 2009;20(6):1217–21.
Waikar SS, Bonventre JV, Creatinine kinetics and the definition of acute kidney injury, J Am Soc Nephrol, 2009;20(3):672–9.
Nguyen MT, Devarajan P, Biomarkers for the early detection of acute kidney injury, Pediatr Nephrol, 2008;23(12):2151–7.
Devarajan P, Emerging biomarkers of acute kidney injury, Contrib Nephrol, 2007;156:203–12.
Devarajan P, Proteomics for biomarker discovery in acute kidney injury, Semin Nephrol, 2007;27:637–51.
Devarajan P, Proteomics for the investigation of acute kidney injury, Contrib Nephrol, 2008;160:1–16.
Devarajan P, Parikh C, Barasch J, Case 31-2007: a man with abdominal pain and elevated creatinine, N Engl J Med, 2008;358(3):312.
Supavekin S, Zhang W, Kucherlapati R, et al., Differential gene expression following early renal ischemia- reperfusion, Kidney Int, 2003;63:1714–24.
Devarajan P, Mishra J, Supavekin S, Patterson LT, Potter SS, Gene expression in early ischemic renal injury: clues towards pathogenesis, biomarker discovery, and novel therapeutics, Mol Genet Metab, 2003;80(4):365–76.
23.
Yuen PST, Jo S-K, Holly MK, et al., Ischemic and nephrotoxic acute renal failure are distinguished by their broad transcriptomic responses, Physiol Genomics, 2006;25:375–86.
24.
Mishra J, Ma Q, Prada A, et al., Identification of neutrophil gelatinase-associated lipocalin as a novel urinary biomarker for ischemic injury, J Am Soc Nephrol, 2003;4:2534–43.
25. 26.
Mishra J, Mori K, Ma Q, et al., Neutrophil Gelatinase- Associated Lipocalin (NGAL): a novel urinary biomarker for cisplatin nephrotoxicity, Am J Nephrol, 2004;24:307–15.
Mori K, Lee HT, Rapoport D, et al., Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from
43. 44. 45. 46. 41. 39. 40. 35. 31. 32. 33. 34. ischemia-reperfusion injury, J Clin Invest, 2005;115:610–21. 27. 28. 29. 30.
Mishra J, Dent C, Tarabishi R, et al., Neutrophil gelatinase- associated lipocalin (NGAL) as a biomarker for acute renal injury following cardiac surgery, Lancet, 2005;365:1231–8.
Parikh CR, Mishra J, Thiessen-Philbrook H, et al., Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery, Kidney Int, 2006;70:199–203.
Portilla D, Dent C, Sugaya T, et al., Liver Fatty Acid-Binding Protein as a biomarker of acute kidney injury after cardiac surgery, Kidney Int, 2008;73:465–72.
Wagener G, Jan M, Kim M, et al., Association between increases in urinary neutrophil-associated lipocalin and acute renal dysfunction after adult cardiac surgery, Anesthesiology, 2006;105:485–91.
Koyner J, Bennett M, Worcester E, et al., Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery, Kidney Int, 2008;74(8):1059–69.
Wagener G, Gubitosa G, Wang S, et al., Urinary neutrophil- associated lipocalin and acute kidney injury after cardiac surgery, Am J Kidney Dis, 2008;52(3):425–33.
Xin C, Yulong X, Yu C, et al., Urine neutrophil gelatinase- associated lipocalin and interleukin-18 predict acute kidney injury after cardiac surgery, Ren Fail, 2008;30:904–13.
Tuladhar SM, Puntmann VO, Soni M, et al., Rapid detection of acute kidney injury by plasma and urinary neutrophil gelatinase-associated lipocalin after cardiopulmonary bypass, J Cardiovasc Pharmacol, 2009;53:261–6.
Haase-Fielitz A, Bellomo R, Devarajan P, et al., Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery—a prospective cohort study, Crit Care Med, 2009;37(2):553–60.
36. 37.
Haase M, Bellomo R, Devarajan P, et al., Novel biomarkers early predict the severity of acute kidney injury after cardiac surgery in adults, Ann Thorac Surg, 2009;88(1):124–30.
Haase-Fielitz A, Bellomo R, Devarajan P, et al., The predictive performance of plasma neutrophil gelatinase- associated lipocalin (NGAL) increases with grade of acute kidney injury, Nephrol Dial Transplant, 2009;24(11):3349–54.
38.
Perry TE, Muehlschlegel JD, Liu KY, et al., CABG Genomics Investigators. Plasma neutrophil gelatinase-associated lipocalin and acute postoperative kidney injury in adult cardiac surgical patients, Anesth Analg, 2010;110(6):1541–7.
Devarajan P, NGAL in acute kidney injury: from serendipity to utility, Am J Kidney Dis, 2008;52:395–9.
Bellomo R, Ronco C, Kellum JA, et al., Acute renal failure- definition, outcome measures, animal modles, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group, Crit Care, 2004;8:R204–12.
McIlroy DR, Wagener G, Lee HT, Neutrophil gelatinase- associated lipocalin and acute kidney injury after cardiac surgery: the effect of baseline renal function on diagnostic performance, Clin J Am Soc Nephrol, 2010;5(2):211–9.
42.
Haase M, Bellomo R, Devarajan P, et al., Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis, Am J Kidney Dis, 2009;54(6):1012–24.
Mishra J, Ma Q, Kelly C, et al., Kidney NGAL is a novel early marker of acute injury following transplantation, Pediatr Nephrol, 2006;21:856–63.
Parikh CR, Jani A, Mishra J, et al., Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation, Am J Transplant, 2006;6:1639–45.
Hall IE, Yarlagadda SG, Coca SG, et al., IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation, J Am Soc Nephrol, 2010;21(1):189–97.
Hollmen ME, Kyllönen LE, Inkinen KA, Lalla ML, Salmela KT, Urine neutrophil gelatinase-associated lipocalin is a marker of graft recovery after kidney transplantation, Kidney Int, 2011;79(1):89–98.
47.
Kusaka M, Kuroyanagi Y, Mori T, et al., Serum neutrophil gelatinase-associated lipocalin as a predictor of organ recovery from delayed graft function after kidney
63. 59. 56. 57. 50. 48.
transplantation from donors after cardiac death, Cell Transplant, 2008;17:129–34.
Bachorzewska-Gajewska H, Malyszko J, Sitniewska E, et al., Neutrophil-gelatinase-associated lipocalin and renal function after percutaneous coronary interventions, Am J Nephrol, 2006;26:287–92.
49.
Bachorzewska-Gajewska H, Malyszko J, Sitniewska E, et al., Neutrophil gelatinase-associated lipocalin (NGAL) correlations with cystatin C, serum creatinine and eGFR in patients with normal serum creatinine undergoing coronary angiography, Nephrol Dial Transplant, 2007;22:295–6.
Ling W, Zhaohui N, Ben H, et al., Urinary IL-18 and NGAL as early predictive biomarkers in contrast-induced nephropathy after coronary angiography, Nephron Clin Pract, 2008;108:c176–81.
51. 52. 53.
Shaker O, El-Shehaby A, El-Khatib M, Early diagnostic markers for contrast nephropathy in patients undergoing coronary angiography, Angiology, 2010;61(8):731–6
Hirsch R, Dent C, Pfriem H, et al., NGAL is an early predictive biomarker of contrast-induced nephropathy in children, Pediatr Nephrol, 2007;22:2089–95.
Gaspari F, Cravedi P, Mandalà M, et al., Predicting cisplatin-induced acute kidney injury by urinary neutrophil gelatinase-associated lipocalin excretion: a pilot prospective case-control study, Nephron Clin Pract, 2010;115(2):c154–60.
54.
Wasilewska A, Zoch-Zwierz W, Taranta-Janusz K, Michaluk- Skutnik J, Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of cyclosporine nephrotoxicity? Pediatr Nephrol, 2010;25(5):889–97.
55.
Wagener G, Gubitosa G, Wang S, et al., Increased incidence of acute kidney injury with aprotinin use during cardiac surgery detected with urinary NGAL, Am J Nephrol, 2008;28:576–82.
Zappitelli M, Washburn KM, Arikan AA, et al., Urine NGAL is an early marker of acute kidney injury in critically ill children, Crit Care, 2007;11:R84.
Wheeler DS, Devarajan P, Ma Q, et al., Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock, Crit Care Med, 2008;36:1297–303.
58.
Makris K, Markou N, Evodia E, et al., Urinary neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in critically ill multiple trauma patients, Clin Chem Lab Med, 2009;47(1):79–82.
Yang HN, Boo CS, Kim MG, et al., Urine neutrophil gelatinase-associated lipocalin: an independent predictor of adverse outcomes in acute kidney injury, Am J Nephrol, 2010;31(6):501–9.
60.
de Geus HR, Bakker J, Lesaffre EM, le Noble JL, Neutrophil gelatinase-associated lipocalin at ICU admission predicts for acute kidney injury in adult patients, Am J Respir Crit Care Med, 2010 (Epub ahead of print).
61.
Siew ED, Ware LB, Gebretsadik T, et al., Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults, J Am Soc Nephrol, 2009;20(8):1823–32.
62.
Cruz DN, de Cal M, Garzotto F, et al., Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population, Int Care Med, 2010;36(3):444–51.
Bagshaw SM, Bennett M, Haase M, et al., Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus non-septic acute kidney injury in critical illness, Int Care Med, 2010;36(3):452–61.
64.
Constantin J-M, Futier E, Perbet S, et al., Plasma neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: a prospective study, J Crit Care, 2010;25(1):176.e1–6.
65.
Niemann CU, Walia A, Waldman J, et al., Acute kidney injury during liver transplantation as determined by neutrophil gelatinase-associated lipocalin, Liver Transplant, 2009;15:1852–60.
66. Nickolas TL, O’Rourke MJ, Yang J, et al., Sensitivity and
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