US Respiratory Disease


Volume 6


Cover image: False-color scanning electron microscope image of tracheal epithelium. © Prof P Motta/Science Photo Library


Managing Editor Tami Hughes


Editor Lucy Wakefield-Smith


Sub-editorial Manager Lisa Glass


Senior Sub-editor Claire Vinent


Technical Editor Patrick Wong


Design Manager Eliza Albie


Artworker Ian Shoobridge


Production Manager Anthony Gibbons


Key Account Director Chris Potten


Medical Sales Director Barney Kent


Publishing Director Fergus Brunning


Editorial Contact Lucy Wakefield-Smith T: +44 (0) 20 7452 5357 F: +44 (0) 20 7452 5050


E: lucy.wakefield-smith@touchbriefings.com


Circulation Contact Miriam Oppenheim


E: miriam.oppenheim@touchbriefings.com


Sales Contact Chris Potten


T: +44 (0) 20 7452 5332 F: +44 (0) 20 7452 5606


E: chris.potten@touchbriefings.com


Association Contact Xue Han


T: +44 (0) 20 7452 5042 F: +44 (0) 20 7452 5606


E: xue.han@touchbriefings.com


US Respiratory Disease acknowledges the financial assistance of the following companies in the publication of this edition: Talecris Biotherapeutics Inc., Roche Diagnostics Corporation, and Siemens Healthcare Diagnostics Inc.


W Michael Alberts, MD, MBA, FCCP


Professor of Oncology and Medicine, University of South Florida College of Medicine


Clifford W Bassett, MD Medical Director, Allergy and Asthma Care of New York


Michael S Blaiss, MD Clinical Professor of Pediatrics and Medicine, University of Tenessee Health Sciences Center


Brian W Carlin, MD


Assistant Professor of Medicine, Drexel University


Thomas B Casale, MD Professor and Associate Chair, University in Omaha


Jonathan Curren, MD Associate Clinical Professor of Medicine, University of California, Los Angeles


Erwin W Gelfand, MD Chairman, Department of Pediatrics, National Jewish Health


Rochelle Goldberg, MD Medical Co-Director, Sleep Medicine Services, Main Line Health System, Pennsylvania


Daniel Ein, MD


Clinical Professor of Medicine, George Washington University School of Medicine


Editorial Board


Harly Greenberg, MD, FCCP, FASM


Professor of Clinical Medicine, Albert Einstein College of Medicine


John Haughney, MD


Research fellow, Department of General Practice, University of Aberdeen


John Heffner, MD Garnjobst Chair of Medical Education, Providence Portland Medical Center, Oregon Health and Science University


Michael A Kaliner, MD Clinical Professor of Medicine, George Washington University


Alan Kaplan MD


Family Physician, Richmond Hill, Ontario


H William Kelly, PharmD Professor Emeritus of Pediatrics, Department of Pediatrics and Pulmonary, University of New Mexico


Eitan Kerem, MD


Associate Professor of Pediatrics, Hadassah Medical School, Hebrew University


Barry A Mizock, MD, FACP, FCCM


Associate Professor Medicine, Rush Medical College, Chicago


Sreedhar Nair, MD


Clinical Professor of Medicine, Yale University


Linda Nici, MD


Director Pulmonary and Critical Care Medicine, Providence Veterans Administration Medical Center


Sairam Parthasarathy, MD Chief of Research, Southern Arizona VA Health Care System


Stephen P Peters, MD, PhD FACP, FAAAAI, FCCP, FCPP


Director of Research, Wake Forest University Health Sciences


Michael Rosenzweig, PhD Professor of Ecology and Evolutionary Biology, University of Arizona


Sat Sharma, MD, FRCPC, FCCP, FACP


Professor and Head, Division of Pulmonary Medicine, University of Manitoba


Terri E Weaver, PhD, RN, CS, FAAN


Professor of Nursing, School of Medicine University of Pennsylvania.


Art Wheeler, MD


Associate professor of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University


US Respiratory Disease wishes to thank the organizations below for their assistance. This does not constitute any official endorsement.


US Respiratory Disease is audited by BPA Worldwide. Published by Touch Briefings. Touch Briefings is the trading name of Business Briefings Ltd, a Touch Group plc company.


All information obtained by Business Briefings Ltd and each of the contributors from various sources is as current and accurate as possible. However, due to human or mechanical errors, Business Briefings Ltd and the contributors cannot guarantee the accuracy, adequacy or completeness of any information, and cannot be held responsible for any errors or omissions, or for the results obtained from the use thereof.


Where opinion is expressed, it is that of the authors and does not necessarily coincide with the editorial views of Business Briefings Ltd. Statistical and financial data in this publication have been compiled on the basis of factual information and do not constitute any investment advertisement or investment advice.


©2010 All rights reserved ISSN:1753-4089


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76  |  Page 77  |  Page 78  |  Page 79  |  Page 80  |  Page 81  |  Page 82  |  Page 83  |  Page 84