Contents


Foreword Steven D Wexner, MD Chief Academic Officer and Chairman, Department of Colorectal Surgery, Cleveland Clinic Florida Special Report


What Should Gastroenterologists Do about Obesity? Amy E Foxx-Orenstein, DO, FACG, FACP


Associate Professor of Medicine, Division of Gastroenterology and Hepatology, and Director, Constipation and Anorectal Disorders, Mayo Clinic Arizona


Upper Gastrointestinal Tract


The Role of Bile Reflux in Barrett’s Esophagus Lisa Cassani, MD1


12 and Michael F Vaezi, MD, PhD, MSc (Epi)2


1. Resident in Internal Medicine; 2. Professor of Medicine and Clinical Director, Department of Gastroenterology and Hepatology, and Director, Clinical Research and Center for Swallowing and Esophageal Disorders, Vanderbilt University Medical Center


Inflammatory Bowel Disease


Clinical and Biological Prognostic Markers in Crohn’s Disease Stephen B Hanauer, MD


Professor of Medicine and Clinical Pharmacology, and Chief, Section of Gastroenterology, Hepatology and Nutrition, University of Chicago Medical Center


The Clinical Syndrome of Pouchitis—Evaluation, Etiology, and Management Kathryn E Coan, MD,1


Jacques P Heppell, MD2 and Jonathan A Leighton, MD3


1. Second-year Surgical Resident; 2. Professor of Surgery; 3. Professor of Medicine, and Chair, Division of Gastroenterology, Divisions of Colon and Rectal Surgery and Gastroenterology, Mayo Clinic Arizona


Irritable Bowel Syndrome


Diagnostic Testing for Irritable Bowel Syndrome Lisa M Davis, PhD,1


John Alsobrook II, PhD,2 27 Cole Harris, MS3 and Mark Pimentel, MD4


1. Vice President Product Development; 2. Vice President Clinical Laboratory Operations; 3. Vice President Discovery, Exagen Diagnostics, Albuquerque; 4. Director, Gastroenterology Motility Program, and Associate Professor of Medicine, Cedars-Sinai Medical Center


Role of Microbiome in Irritable Bowel Syndrome Amir Nejad, MD1


and Mark Pimentel, MD, FRCP(C)2


1. Internal Medicine Resident; 2. Director, GI Motility Program, and Director, GI Motility Laboratory, Cedars-Sinai Medical Center


Probiotics


Clinical Case Study—Multispecies Probiotic Supplement Minimizes Symptoms of Irritable Bowel Syndrome


Rup Nagala, MD1 and Chittaranjan Routray, MBBS2


1. Clinical Assistant Professor, Department of Family Medicine, University of North Dakota; 2. Research Fellow, Mayo Clinic College of Medicine


4 US GASTROENTEROLOGY & HEPATOLOGY REVIEW 36 31 23 17 10 8


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