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Full-volume Color Flow Quantification in Mitral Regurgitation


This allows automatic visualization of 3D PISA surface and anatomic EROA, with expected higher accuracy of the subsequent regurgitant volume calculation when compared with the conventional manual tracing methods. Extensive in vitro experiments established the accuracy of this method in measuring surface area, EROA, and regurgitant flow, especially when compared with the calculations obtained from the conventional spherical approximation. Studies regarding in vivo validation of this technique for MR quantification are currently in progress and there is great expectation regarding their results.


From the concept to the main principals of application, which overcome the well-known limitations of 2D and conventional 3D echocardiography, assessment of the new PISA methodology by full-volume color flow


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quantification of MR promises to be a more precise approach to the assessment of the severity of valvular pathology, capable of changing our way of performing echocardiography.


Conclusions


MR is a common pathology requiring precise evaluation for appropriate clinical decision-making, and the use of 3D echocardiography is overcoming the limitations of 2D echocardiography. A new methodology is being developed to further improve MR quantification: 4D instantaneous full-volume color flow quantitative software, allowing the automatic calculation of the flow convergence area and aiming to provide a more precise and easier approach to the assessment of the severity of valve regurgitation. It is validated in vitro, and further in vivo validation will allow its use in clinical practice. n


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