Identifying Genetic Susceptibility Loci for Hypertension in African Americans
genetics of blood pressure and hypertension traits, Am J Hypertens, 2011;24:392–400.
19. Kato N, Takeuchi F, Tabara Y, et al., Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians, Nat Genet, 2011;43:531–8.
20. Manolio TA, Collins FS, Cox NJ, et al., Finding the missing heritability of complex diseases, Nature, 2009;461:747–53.
21. Ji W, Foo JN, O’Roak BJ, et al., Rare independent mutations in renal salt handling genes contribute to blood pressure variation, Nat Genet, 2008;40:592–9.
22. Adeyemo A, Gerry N, Chen G, et al., A genome-wide association study of hypertension and blood pressure in African Americans, PLoS Genet, 2009;5:e1000564.
23. Fox ER, Young JH, Li Y, et al., Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study, Hum Mol Genet, 20:2273–84.
24. Lettre G, Palmer CD, Young T, et al., Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project, PLoS Genet, 2011;7:e1001300.
25. Zhu X, Luke A, Cooper RS, et al., Admixture mapping for hypertension loci with genome-scan markers, Nat Genet, 2005;37:177–81.
26. Deo RC, Patterson N, Tandon A, et al., A high-density admixture scan in 1,670 African Americans with hypertension, PLoS Genet, 2007;3:e196.
27. Zhu X, Cooper RS, Admixture mapping provides evidence of association of the VNN1 gene with hypertension, PLoS One, 2007;2: e1244.
28. Shriner D, Adeyemo A, Ramos E, et al., Mapping of disease-associated variants in admixed populations, Genome Biol, 2011;12:223.
29. Price AL, Tandon A, Patterson N, et al., Sensitive detection of chromosomal segments of distinct ancestry in admixed
populations, PLoS Genet, 2009;5:e1000519.
30. Pasaniuc B, Zaitlen N, Lettre G, et al., Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium, PLoS Genet, 2011;7:e1001371.
31. Zhu X, Young JH, Fox E, et al., Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium, Hum Mol Genet, 2011;20:2285–95.
32. Kopp JB, Smith MW, Nelson GW, et al., MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis, Nat Genet, 2008;40:1175–84.
33. Kao WH, Klag MJ, Meoni LA, et al., MYH9 is associated with nondiabetic end-stage renal disease in African Americans, Nat Genet, 2008;40:1185–92.
34. Genovese G, Friedman DJ, Ross MD, et al., Association of trypanolytic ApoL1 variants with kidney disease in African Americans, Science, 2010;329:841–5.
US NEPHROLOGY
109
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84