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Glaucoma Figure 1: abee® Glaucoma Tip


Figure 2: Penetration of the High-frequency Tip (A) and Penetration up to 1 mm Nasally into the Sclera (B)


AB Cornea


Juxtacanal. tissu


Sclera Scleral spur


ca


Descement membrane


Schwalbe ring


Direction of the STT ab interno tip application


Iris cp Figure 3: Thalamus 0.3 mm High and 0.6 mm Wide


Figure 4: Primary Open-angle Glaucoma Average Level of Intraocular Pressure


Figure 5: Juvenile Glaucoma Average Level of Intraocular Pressure


10 20 30 40 50


15 25 35 45


5 0


49 48 Time in months


Figure 6: Primary Open-angle Glaucoma Percentage of Patients Reaching Specified Intraocular Pressure Levels


100


10 30 50 70 90


20 40 60 80


0 <15 <16 IOP = intraocular pressure.


72 months was 14.7 ± 1.8 mmHg (range 10–21 mmHg) for primary open-angle glaucoma and 13.2 ± 1.3 mmHg (range 12–15 mmHg) for juvenile glaucoma. The IOP drop for both groups was statistically highly significant (p<0.001) at all measured post-operative intervals (see Figures 4 and 5). Pressure reduction at any time of standardised follow-up was statistically significant compared with pre-operative data at a level of α<0.03 (Bonferroni-corrected). In the juvenile


18 <17 <18 <19 Mean diurnal IOP (mmHg) <20 <21 <22 86.8 76 67.2 60.4 52.8 94 98.1 100 44 43 42


41 40


39 38 37 36 35 34 33 32 31 30 29 28 27 26 25 24 23


glaucoma group, with five patients there are not enough cases to get conclusive statistics but the results show the tendency.


At month 72 after surgery, 52.8 % of patients with open-angle glaucoma had an IOP <15 mmHg, 76 % had an IOP <18 mmHg and 79.2 % had an IOP <21 mmHg (see Figure 6); 80 % of patients with juvenile glaucoma had an IOP <15 mmHg and 100 % had an IOP <18 mmHg. After 72 months, 84.9 % achieved >20 % reduction in IOP and 77 % of treated patients with open-angle glaucoma achieved >30 % reduction of IOP.


EUROPEAN OPHTHALMIC REVIEW 22 21 20 19 18 0 47 46 45 20 10 30 50


10 20 30 40 50


15 25 35 45


5 0


Time in months


Figure 7: Primary Open-angle Glaucoma Pre-operative and Post-operative Level of Intraocular Pressure after 48 Months of Follow-up


mmHg 50


51 52 53 40 1 2 3 4 5 6 7 8 9 10 11 12


16 15 14 13


17


Patients (%)


mmHg


mmHg


preop


1d


2d


3d


4d


1 month 7d


57 months 54 months 51 months 48 months 45 months 42 months 39 months 36 months 33 months 30 months 27 months 24 months 21 months 18 months 15 months 12 months 9 months 6 months 3 months


preop


66 months 63 months 60 months


1d


2d


69 months 72 months


3d


4d


1 month 7d


57 months 54 months 51 months 48 months 45 months 42 months 39 months 36 months 33 months 30 months 27 months 24 months 21 months 18 months 15 months 12 months 9 months 6 months 3 months


66 months 63 months 60 months


69 months 72 months


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